Cefuroxime: A Clinical Evaluation
نویسندگان
چکیده
منابع مشابه
Evaluation of the use of cefuroxime and cefuroxime axetil in an intravenous-oral stepdown program.
OBJECTIVE To characterize cefuroxime and cefuroxime axetil use under the influence of a parenteral-to-oral (iv-po) stepdown program. DESIGN Open single-center retrospective review. SETTING Tertiary care teaching and referral Canadian hospital with 1100 beds. PATIENTS A random sample of 78 patients receiving cefuroxime was compared with a random sample of 50 patients receiving iv-po cefuro...
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Cefuroxime, a new antibiotic derived from cephalosporin-C which is very stable in the presence of beta-lactamases produced by Gram-negative organisms, was used to treat 856 male patients and 340 female patients with uncomplicated gonorrhoea. In men the drug was used in three different doses, 1.5 g, 1 g, and 750 mg plus 1 g probenecid; in women 1 g and 750 mg cefuroxime plus 1 g probenecid was u...
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متن کاملCefuroxime: human pharmacokinetics..
Single doses of cefuroxime, a new parenteral cephalosporin, were given to 44 normal male subjects. Doses of 0.25, 0.5, 0.75, or 1.0 g were given intramuscularly to 33 volunteers. Mean peak serum concentrations of 14.8, 25.7, 34.6, and 40.0 mug/ml were assayed at 29 to 45 min, and measurable levels were present 8 h after the 0.5-g and higher doses. Single intravenous bolus doses of 0.25, 0.5, or...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1977
ISSN: 0035-9157
DOI: 10.1177/00359157770700s923